Monday, January 25, 2010

Aging

Aging can be slowed.

It's a blunt statement but scientists have found certain drugs that will slow the destruction of cells, contributing to the overall health of an individual. The drug SIR2 has been shown to keep DNA's structure and slow the creation of waste DNA which eventually destroys the cell.

Scientist David Sinclair describes the effects of SIR2 saying, "we might be able to make drugs...to treat diseases of aging, such as cancer, heart disease, diabetes and even Alzheimer's disease".

Controlling the oxidative levels of the brain has also been hypothesised to slow aging. Many methods are being used to attempt to slow the creation of oxidants through metabolism. Calorie restriction is the most effective method known at the time and it is also how SIR2 is tested. The cell with SIR2 was fed with less calories and SIR2's backup system managed to keep the cell in better condition then when it was fed the required amount of calories.

So, with less calories, a cell could lower its oxidant rate and remain healthier than its original self.

Ethically, these decisions are disliked by many scientists as they are essentially "playing God". However, others claim that science is the means to improve human life by whatever means necessary.

Websites:
http://www.pbs.org/wgbh/nova/sciencenow/3401/01.html
http://www.ncbi.nlm.nih.gov/books/bv.fcgi?rid=coffeebrk.chapter.653

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